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Erik Lamela bagged a hat-trick as Spurs secured top spot in Europa League Group J with a sizzling 4-1 win over Monaco at White Hart Lane.
Needing just a point to finish above second-placed Anderlecht, the hosts flew out of the traps and were ahead within two minutes when Lamela made no mistake from Ben Davies' centre.
Nothing less than a victory was required for Monaco to have any chance of progressing to the knockout stages but their tough task was made a near-impossible one when Lamela netted his second soon after.
The Argentine completed his hat-trick on 37 minutes to put the game beyond the Ligue Un side.
Stephan El Shaarawy gave the visitors hope just after the hour-mark and they could have been right back in the contest minutes later but Nabil Dirar somehow headed wide when unmarked at the far post.
The chances of an unlikely comeback were ended on 78 minutes when Tom Carroll to seal an impressive win for the Premier League side.
With Spurs already safely through to the last 16, Mauricio Pochettino made seven changes to his starting line-up, and his makeshift side made the perfect start as Ben Davies crossed for Lamela who slotted home in just the second minute.
The hosts were rampant and on 15 minutes Lamela doubled their tally courtesy of an error from the Monaco goalkeeper, who allowed the Argentine winger's low effort to squirm under his body and into the back of the net to leave the French side with a mountain to climb.
The north Londoners continued to dominate and Son came close to scoring a third with a spectacular effort which was just off target before Tom Carroll curled wide from the edge of the box.
Eight minutes before the break Spurs effectively sealed the three points when Clinton N'Jie won the ball in his own half and the ball made its way to Son who turned and played in Lamela, the forward kept his cool to finish past Subasic and complete his hat-trick.
Spurs could and should have extended their lead further still when Son fed Joshua Onomah and the youngster evaded a challenge before shooting but his effort was scuffed and Subasic saved easily.
Monaco were given hope when Kylian Mbappe picked out Stephan El Shaarawy on the edge of the area and the striker on loan from AC Milan coolly found the bottom corner with a curled finish.
Drirar then squandered a great opportunity to reduce the deficit to a single goal before Carroll showed a cool head to skip past a defender and finish from a tight angle.