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Arsenal are through to the last 16 of the Champions League as Group A winners after beating FC Basel 4-1 at St-Jakob Park.
The victory, coupled with Ludogorets' 2-2 draw with Paris Saint-Germain at the Parc de Princes, sees the Gunners progress as group winners, with Unai Emery's side having to settle for the runners-up spot.
Lucas Perez netted a hat-trick, with Alex Iwobi adding a fourth, as Arsenal go through the group stage unbeaten for the first time since 2006, the year they finished runners-up in the Champions League.
Perez, back to full fitness following the ankle injury he suffered on EFL Cup duty on 25 October, opened the scoring on eight minutes after drifting past defender Adama Traore and finishing Kieran Gibbs' cross at the far post.
The £17m deadline day signing from Deportivo La Coruna made it two goals and two assists from 44 minutes of Champions League football with his second goal of the night on 16 minutes, from another low Gibbs cross from the left channel.
And the 28-year-old Spanish forward completed his hat-trick two minutes into the second half, with a first-time shot past Basel goalkeeper Tomas Vaclik, following a rare miscontrol of a Gibbs pass by Sanchez.
With the strike, Perez becomes the sixth Arsenal player to score a Champions League hat-trick, following Thierry Henry, Niclas Bendtner, Danny Welbeck, Olivier Giroud and Mesut Ozil.
Iwobi then made it 4-0 on 53 minutes with a close-range finish from Ozil's cross following more impressive build-up play from Sanchez.
But the Swiss champions netted a consolation on 78 minutes as Seydou Doumbia took advantage of a Rob Holding mistake to net his 26th goal in European football from 42 games.
Group winners Arsenal will face either Benfica, Bayern Munich, Bayer Leverkusen, Borussia Dortmund or Real Madrid, Porto or Copenhagen, and one of Juventus, Sevilla or Lyon after Monday's last-16 draw.
Bulgarian champions Ludogorets progress to the Europa League following their impressive 2-2 draw with the French champions in Paris.
Virgil Misidjan headed the visitors into the lead on 15 minutes, but Edinson Cavani equalised with an overhead kick just after the hour mark.
But Wanderson restored Ludogorets' advantage on 69 minutes after a mistake by Marquinhos, and Angel Di María's late equaliser was not enough for PSG to pip Arsenal at the top of the table.
Photo (Getty Images/Patrick Hertzog)
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