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Striker Charlie Austin is set to make his Southampton debut at Manchester United on Saturday (LIVE on Setanta 1).
The 26-year-old, who has not played since mid-December due to a hamstring injury, moved to St Mary's from QPR in a £4m deal last weekend.
The former Swindon and Burnley player scored 18 goals for QPR in the Premier League last season but was unable to keep them in the top flight.
He had been valued at £12m by the Loftus Road club who turned down a number of offers for him during the summer.
"I was a little worried because Charlie had a hamstring injury before we signed him, but he had all the medical tests and took part in all the training sessions this week," Southampton boss Ronald Koeman said.
"We had to test him to know he is available and on his fitness tests he is as good as the rest of the players. I wasn't expecting it so quickly but it's nice to be surprised.
"He will be in the squad this weekend."