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Jonathan Sexton will captain Leinster for the first time as Coach Leo Cullen has rung the changes for their final Champions Cup pool game away to Wasps.
Cullen has made 11 changes to the team that comprehensively beat Bath at the RDS last time out with only Zane Kirchner, Dave Kearney, Rhys Ruddock and Jordi Murphy retained in the XV.
The Leinster boss has resisted the temptation to stick with the "Cubs" after their impressive win last time out.
With the return of Rob Kearney, Kirchner moves to the right wing, with Dave Kearney continuing on the left.
In the centre, Noel Reid is paired with Luke Fitzgerald while Eoin Reddan Johnny Sexton are selected in the halfbacks.
Jack McGrath, Sean Cronin and Marty Moore make up the front row ahead of Devin Toner and Rhys Ruddock in the second.
In the back row, Jamie Heaslip returns at eight, with Dominic Ryan and Jordi Murphy completing the pack as Leinster look to avenge their 33-6 home defeat to Wasps in the opening round of the competition.
Leinster XV (v Wasps): Rob Kearney, Zane Kirchner, Luke Fitzgerald, Noel Reid, Dave Kearney, Johnny Sexton (C), Eoin Reddan; Jack McGrath, Sean Cronin, Marty Moore, Devin Toner, Rhys Ruddock, Dominic Ryan, Jordi Murphy, Jamie Heaslip.
Replacements: Richardt Strauss, Peter Dooley, Michael Bent, Ross Molony, Josh van der Flier, Isaac Boss, Cathal Marsh , Ben Te'o.