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Leinster fullback Jordan Larmour has been handed his first start in the European Champions Cup by coach Leo Cullen.
Larmour made substitute appearances in rounds three and four, with his performances, and those against Munster and Ulster in the Pro 14, earning him a starting berth against Glasgow at the RDS on Sunday, kick-off 1pm.
James Lowe will also make his first start in the tournament after three tries in two appearances in the Pro 14 for the New Zealander.
In midfield, Garry Ringrose is ruled out due to injury, with Robbie Hehnshaw moving out to 13, and Isa Nacewa slotting in at 12.
Tadhg Furlong is fit to start at tighthead after successfully coming through return-to-play protocols and an elbow injury sustained against Ulster.
Hooker Bryan Byrne is named on the bench, and will also make his European debut should be called upon. James Ryan is the replacement lock after recovering from injury.
Sean O'Brien continues to be ruled out due to a hip issue, and underwent a procedure to fix the issue this week; his return is likely to be during the Six Nations. Adam Byrne is also undergoing a procedure on his knee, following an injury in the Guinness Series - his return date is as yet unconfirmed.
Leinster: Jordan Larmour; Fergus McFadden, Robbie Henshaw, Isa Nacewa (c), James Lowe, Johnny Sexton, Luke McGrath; Jack McGrath, Seán Cronin, Tadhg Furlong, Devin Toner, Scott Fardy, Jordi Murphy, Josh van der Flier, Jack Conan.
Replacements: Bryan Byrne, Cian Healy, Andrew Porter, James Ryan, Dan Leavy, Nick McCarthy, Ross Byrne, Rob Kearney.
The fifth round of the European Rugby Champions Cup takes place over the weekend of 12-14 January, and you can watch the best of the action on BT Sport on the eir Sport package. On Friday, 12 January, Premiership side Bath host Pro 14 side Scarlets at the Recreation Ground [BT Sport 2, kick-off 7.45pm], then on Saturday, 13 January, Premiership leaders Exeter Chiefs take on Top 14 side Montpellier at Sandy Park [BT Sport 2, kick-off 3.15pm], and Pro 14 side Ospreys meet Premiership side Saracens at the Liberty Stadium later the same evening [BT Sport 3, kick-off 7.45pm].
On Sunday, 14 January, Top 14 side Toulon take on Benetton at the Stade Felix Mayol [BT Sport 2, kick-off 2pm], while Top 14 side Castres host Premiership side Leicester Tigers at the Stade Pierre Fabre [BT Sport 2, kick-off 6.30pm].
Image: Inpho/ Ryan Byrne
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