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Georgino Wijnaldum netted twice as relegated Newcastle beat Tottenham 5-1 at St James Park, to condemn Mauricio Pochettino's side to third place behind Arsenal in the Premier League table.
Tottenham, so long the only challengers to Leicester City at the top of the table, drop below their North London neighbours after taking just two points from their final four matches against West Brom, Chelsea, Southampton and Newcastle.
Arsenal finish ahead of Spurs for a 21st successive season after a 4-0 win over Aston Villa, with Olivier Giroud netting a hat-trick at the Emirates Stadium before Villa goalkeeper Mark Bunn put through his own goal in injury-time.
At St James' Park, Wijnaldum opened the scoring on 19 minutes from Aleksandar Mitrovic's pass, then the Serb doubled the lead on 39 minutes with a header from Moussa Sissoko's cross.
Erik Lamela pulled one back for Spurs on the hour when he beat Newcastle goalkeeper Karl Darlow at his near post, before Mitrovic was sent off seven minutes later following a horror tackle on Kyle Walker.
Newcastle restored their two-goal advantage on 73 minutes through Wijnaldum's penalty, after referee Anthony Taylor pointed to the spot following Sissoko's theatrical tumble over Christian Eriksen's tackle.
Substitute Rolando Aarons and defender Daryl Janmaat then netted two goals in two minutes to complete the rout.
Champions Leicester City finish the season 10 points clear of second-placed Arsenal following a 1-1 draw with 2015 champions Chelsea at Stamford Bridge.
Cesc Fabregas opened the scoring from the penalty spot on 66 minutes, before Danny Drinkwater levelled on 82 minutes with an emphatic drive from 30 yards out.
Everton ended a disappointing campaign on an upbeat note with a 3-0 victory over Norwich City at Goodison Park, thanks to goals from James McCarthy, a penalty from Leighton Baines following Robbie Brady's foul on Romelu Lukaku, and Kevin Mirallas' late tap-in.
The victory see The Toffees finish 11th, while already-relegated Norwich end the season in 19th place.
News of the day's other Premier League matches can be found here.