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Leo Cullen has kept faith with the majority of the starting XV that defeated Wasps for Sunday's European Champions Cup semi-final against ASM Clermont.
Fresh from being named in the British and Irish Lions squad, Sean O'Brien has been ruled out of the game due to a tightness in his hamstring, with the Ireland international set to be assessed ahead of the visit of Glasgow in the Guinness PRO12.
Isa Nacewa will earn his 50th European cap for the province after being named on the left wing as Fergus McFadden comes into the side on the right wing for his 150th Leinster appearance. The back three is completed by Joey Carbery, who will start at full back.
Robbie Henshaw and Garry Ringrose renew their partnership in the centre as Luke McGrath and Johnny Sexton team up in the half-back line.
Jack McGrath, Richardt Strauss and Tadhg Furlong are named in the front row as Devin Toner once again locks down with Hayden Triggs in the second row.
Rhys Ruddock comes in at blindside flanker, with Dan Leavy moving to openside and Jack Conan continuing at number eight.
Meanwhile, lock Sébastien Vahaamahina, hooker Benjamin Kayser and prop Davit Zirakashvili have all been passed fit for Clermont after overcoming their respective injury concerns.
Leinster (XV v ASM Clermont): J Carberry; F McFadden, G Ringrose, R Henshaw, I Nacewa; J Sexton, L McGrath; J McGrath, R Strauss, T Furlong, D Toner, H Triggs, R Ruddock, D Leavy, J Conan.
Replacements: S Cronin, P Dooley, M Bent, R Molony, J van der Flier, J Gibson-Park, R Byrne, Z Kirchner.
ASM Clermont (XV v Leinster): S Spedding; D Strettle, A Rougerie, R Lamerat, N Abendanon; C Lopez, M Parra; R Chaume, B Kayser, D Zirakashvili, A Iturria, S Vahaamahina, D Chouly, P Yato, F Lee.
Replacements: J Ulugia, R Falgoux, A Jarvis, P Jedrasiak, A Lapandry, L Radosavljevic, P Fernandez, D Penaud.
Munster will face last year's winners Saracens in the European Champions Cup semi-final at the Aviva Stadium on April 22 exclusively live on BT Sport, part of the eir Sport pack.