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Annie Power heads the 13 possibles for Tueday's Stan James Champion Hurdle at the Cheltenham Festival.
The mare has been supplemented for the two-mile championship after stable companion Faugheen was ruled out through injury and she is likely to take her chance for trainer Willie Mullins.
The County Carlow handler has left her in the OLBG Mares' Hurdle on the same afternoon, but the trainer has intimated that he will allow her to take her chance in the Champion.
As well as Annie Power, Mullins has entered Sempre Medici and Nichols Canyon, while Identity Thief has stood his ground for Henry de Bromhead.
Nicky Henderson has four possibles with Notch, Peace And Co, Hargam, Sign Of A Victory and My Tent Or Yours all engaged, with Old Guard a possible for Paul Nicholls.
The New One will bid to make it third-time lucky in the feature when he takes his chance for Nigel Twiston-Davies, while Robert Walford will rely on Camping Ground. Neil King has added National Spirit Hurdle winner Lil Rockerfeller.
There are 25 entries for the Sky Bet Supreme Novices' Hurdle, the first race of the 2016 National Hunt Festival.
Min is the favourite to land the opener for Mullins, although he also has Yorkhill, Bellshill Babbling Stream, Bachasson, Bello Conti, Long Dog, Petit Mouchoir and Thomas Hobson entered.
Last year's Champion Bumper winner Moon Racer could make his hurdling debut in the race for David Pipe.
Douvan won the Supreme Novices' Hurdle12 months ago and he will be looking for a second Cheltenham success when he faces up to a dozen rivals in the Racing Post Arkle Challenge Trophy.
He has impressed this season and is the hot favourite to hand Mullins another Festival successs. The Irish handler also has the option of running Shaneshill and Outlander.
Sizing Codelco and Sizing John could take their chance for Genry De Bromhead, while Gordon Elliott's The Game Changer completes the Irish interest.
Nicky Henderson has left in L'Ami Serge, although he has hinted that he will bid for the JLT Novices' Chase instead. He also has Vaniteux entered.
Neil Mulholland is double-handed with both Baltimore Rock and Fox Norton entered as Azo, Garde La Victoire, On Tour and Zamdy Man complete the possible entries.
The OBLG Mares' Hurdle has attracted 26 entries at the six-day stage.
Annie Power remains engaged by Mullins is almost certain to retire on Vroum Vroum Mag, who is unbeaten in eight starts.
Other possibles include Flute Bowl, Gitane Du Berlais, Whiteout Aurore D'Estruval and Jessber's Dream.