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Louis van Gaal has injury concerns ahead of Manchester United's Premier League tie with West Ham.
Defender Marcos Rojo is facing a spell on the sidelines after he dislocated his should in training on Wednesday.
The 25-year-old suffered the same injury against Manchester City last season and went on to miss four weeks, but van Gaal does not know how long he will be without the Argentine for this time.
"It was already in the media – Rojo has been injured. It’s his shoulder, the same as last year, in a training session. It’s very unfortunate, also in the position of Luke Shaw so I have a great problem," the manager told MUTV.
United will also be without captain Wayne Rooney for the visit of West Ham to Old Trafford.
Rooney was forced off in Saturday's match against Leicester City and van Gaal has confirmed he will miss the weekend's game due to a 'nasty' ankle injury.
"Wayne's injury is more heavy than we thought and it's a nasty injury," he said.
"When we go on it’s been getting worse. We have to let him train to make the ankle stronger, that’s very important. I cannot say [how long he'll be out] because the doctor shall decide that with Wayne of course. He is training well in the rehabilitation."
Van Gaal is currently without six players and with the busy festive period fast approaching he admits he has been forced to give his squad time off to rest.
"The week after next we have two weeks that we can have more recovery. I have already given the players two days off this week," he explained.
"I am giving them a lot of rest because I think it is necessary now, nevertheless we have six injuries most of which are contact injuries. You cannot avoid those because football is a sport with direct resistance. We are unlucky I have to say."