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The Ireland team to face South Africa in the second Test shows five changes from the starting XV for last Saturday’s historic first Test win in Cape Town.
CJ Stander's one-match suspension means he misses out on this week's Test at Ellis Park and his place at blindside flank goes to Iain Henderson, who moves from the second row.
Uncapped Quinn Roux comes in to lock down alongside Devin Toner as Rhys Ruddock joins Henderson and Jamie Heaslip in the back row for his first start since November 2014.
Tadhg Furlong comes into the front row for his first international start and he will start alongside captain Rory Best and Jack McGrath.
Jared Payne is retained at full-back but Craig Gilroy is named on the left wing. Andrew Trimble takes his place on the right, while Robbie Henshaw will start in midfield alongside Stuart Olding.
Conor Murray and Paddy Jackson are retained at half-back.
As well as the changes to the starting XV, Schmidt has made changes to the bench with Sean Reidy and Tiernan O'Halloran joining by Richardt Strauss, Dave Kilcoyne, Finlay Bealham, Donnacha Ryan, Kieran Marmion and Ian Madigan.
Ireland (XV v South Africa): J Payne; A Trimble, R Henshaw, S Olding, C Gilroy; P Jackson, C Murray; J McGrath, R Best, T Furlong, D Toner, Q Roux, I Henderson, R Ruddock, J Heaslip.
Replacements: R Strauss, D Kilcoyne, F Bealham, D Ryan, S Reidy, K Marmion, I Madigan, T O'Halloran.
Conor O'Brien will make his Leinster debut in Friday's Pro 14 game against Conference A leaders Glasgow Warriors at Scotstoun Stadium.
Munster have made ten changes for Friday's Pro 14 game against Dragons at Musgrave Park.
Ireland head coach Joe Schmidt says "there is no policy" to omit foreign-based players from the national team.
Ireland head coach Mark Aston says Michael Morgan faces a fitness test on Friday ahead of Sunday''s Rugby League World Cup game against Papua New Guinea.
South African lock Jean Kleyn is looking forward to working with Munster's "exceptional" new head coach Johann van Graan.
Shay Given says Joe Hart's emotional TV interview following last weekend's draw at Crystal Palace will be appreciated by the West Ham fans.
Crystal Palace striker Christian Benteke could make his first-team return against Everton at Selhurst Park on 18 November, according to Eagles' boss Roy Hodgson...