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Arsenal midfield Tomas Rosicky may have played his last game for the Gunners after he was ruled out for up to three months because of a thigh problem.
Rosicky, who has played just 19-minutes this season, suffered a partial tear of a tendon in the FA Cup win over Burnley last Saturday.
The 35-year-old is out of contract in the summer and he is now in a race against time to be fit again before the end of the season.
Asked if Rosicky had played his last game for Arsenal, Wenger said: "I hope not but the injury is quite a serious one. He will not need surgery."
Meanwhile, there was some good news for Arsenal fans with the news that Danny Welbeck is expected to make his return from injury in an under-21 game on Friday.
Welbeck has been sidelined since April 2015 after injuring himself in a 0-0 draw with Chelsea, but he is close to making a return to first team action.
"He needs to play two or three games before coming back to the first team. He has been out for 10 months," said Wenger.
"In the next three weeks he should be available."